Getting to know the nitrogen next door: HNMBC measurements of amino sugars

► 1H-15N-HMBC is useful for characterization of amino sugars. ► The modified IMPACT-HNMBC gives superior resolution and sensitivity. ► 1H-15N-HMBC detects 15N even when HSQC fails due to fast exchange. ► Spectra of N-acetylated sugars show 1JND modulation in the indirect dimension.