Variable angle NMR spectroscopy and its application to the measurement of residual chemical shift anisotropy

► Introduction of variable angle NMR (VA-NMR) for samples partially oriented within a stretched gel. ► Measurement of anisotropic NMR parameters within single sample. ► Fully accessible range of angles between gel stretching axis and static magnetic field. ► Detailed analysis of RCSA measurement in a single sample using VA-NMR. ► Proof of principle with RCSA measurement on strychnine in PDMS/CDCl3 as test sample.