کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5406864 | 1393192 | 2009 | 11 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
A uniplanar three-axis gradient set for in vivo magnetic resonance microscopy
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی تئوریک و عملی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: A uniplanar three-axis gradient set for in vivo magnetic resonance microscopy A uniplanar three-axis gradient set for in vivo magnetic resonance microscopy](/preview/png/5406864.png)
چکیده انگلیسی
We present an optimized uniplanar magnetic resonance gradient design specifically tailored for MR imaging applications in developmental biology and histology. Uniplanar gradient designs sacrifice gradient uniformity for high gradient efficiency and slew rate, and are attractive for surface imaging applications where open access from one side of the sample is required. However, decreasing the size of the uniplanar gradient set presents several unique engineering challenges, particularly for heat dissipation and thermal insulation of the sample from gradient heating. We demonstrate a new three-axis, target-field optimized uniplanar gradient coil design that combines efficient cooling and insulation to significantly reduce sample heating at sample-gradient distances of less than 5Â mm. The instrument is designed for microscopy in horizontal bore magnets. Empirical gradient current efficiencies in the prototype coils lie between 3.75Â G/cm/A and 4.5Â G/cm/A with current and heating-limited maximum gradient strengths between 235Â G/cm and 450Â G/cm at a 2% duty cycle. The uniplanar gradient prototype is demonstrated with non-linearity corrections for both high-resolution structural imaging of tissue slices and for long time-course imaging of live, developing amphibian embryos in a horizontal bore 7Â T magnet.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Magnetic Resonance - Volume 200, Issue 1, September 2009, Pages 38-48
Journal: Journal of Magnetic Resonance - Volume 200, Issue 1, September 2009, Pages 38-48
نویسندگان
Andrey V. Demyanenko, Lin Zhao, Yun Kee, Shuyi Nie, Scott E. Fraser, J. Michael Tyszka,