کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5407428 1393216 2007 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Nonlinear magnetic field gradients can reduce SAR in flow-driven arterial spin labeling measurements
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی تئوریک و عملی
پیش نمایش صفحه اول مقاله
Nonlinear magnetic field gradients can reduce SAR in flow-driven arterial spin labeling measurements
چکیده انگلیسی
This work describes how custom-built gradient coils, designed to generate magnetic fields with amplitudes that vary nonlinearly with position, can be used to reduce the potential for unsafe tissue heating during flow-driven arterial spin labeling processes. A model was developed to allow detailed analysis of the adiabatic excitation process used for flow-driven arterial water stimulation with elimination of tissue signal (FAWSETS) an arterial spin labeling method developed specifically for use in skeletal muscle. The model predicted that, by adjusting the amplitude of the gradient field, the specific absorption rate could be reduced by more than a factor of 6 while still achieving effective labeling. Flow phantom measurements and in vivo measurements from exercising rat hind limb confirmed the accuracy of the model's predictions. The modeling tools were also applied to the more widely used continuous arterial spin labeling (CASL) method and predicted that specially shaped gradients could allow similar reductions in SAR.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Magnetic Resonance - Volume 185, Issue 1, March 2007, Pages 94-102
نویسندگان
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