کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5407780 | 1393230 | 2006 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Importance of volume limitation for tissue redox status measurements using nitroxyl contrast agents: A comparison of X-band EPR bile flow monitoring (BFM) method and 300Â MHz in vivo EPR measurement
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی تئوریک و عملی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Importance of volume limitation for tissue redox status measurements using nitroxyl contrast agents: A comparison of X-band EPR bile flow monitoring (BFM) method and 300Â MHz in vivo EPR measurement Importance of volume limitation for tissue redox status measurements using nitroxyl contrast agents: A comparison of X-band EPR bile flow monitoring (BFM) method and 300Â MHz in vivo EPR measurement](/preview/png/5407780.png)
چکیده انگلیسی
Methods proposed for in vivo redox status estimation, X-band (9.4Â GHz) electron paramagnetic resonance (EPR) bile flow monitoring (BFM) and 300Â MHz in vivo EPR measurement, were compared. The spin probe 3-carbamoyl-2,2,5,5-tetramethylpyrrolidine-1-oxyl (carbamoyl-PROXYL) was utilized for both methods, due to its suitable lipophilicity. EPR signal decay of a nitroxyl spin probe in the bile flow and in the liver region (upper abdomen) of several rat groups with different selenium status were measured by both the BFM and the in vivo EPR method, respectively. The nitroxyl radical clearance measured with in vivo EPR method may be affected not only by the redox status in the liver but also by information from other tissues in the measured region of the rat. On the other hand, the time course of nitroxyl radical level in the bile flow of rats was found to be a reliable index of redox status. Measurement site and/or volume limitation, which was achieved by the BFM method in this paper, is quite important in estimating reasonable EPR signal decay information as an index of tissue/organ redox status.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Magnetic Resonance - Volume 181, Issue 1, July 2006, Pages 107-112
Journal: Journal of Magnetic Resonance - Volume 181, Issue 1, July 2006, Pages 107-112
نویسندگان
Iori Ui, Aya Okajo, Kazutoyo Endo, Hideo Utsumi, Ken-ichiro Matsumoto,