کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5499756 | 1533629 | 2017 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Impact of time delay in a stochastic gene regulation network
ترجمه فارسی عنوان
تأثیر تاخیر زمانی در یک شبکه تنظیم مقررات تصادفی
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
فیزیک و نجوم
فیزیک آماری و غیرخطی
چکیده انگلیسی
In this paper, stationary probability distribution (SPD), mean first passage time (MFPT) and stochastic resonance (SR) phenomenon of an abstract model of the Myc/E2F/MiR-17-92 network with time delay and cross-correlation noise sources are investigated. The impacts of time delay Ï, additive and multiplicative noise intensities Q and D, and cross-correlation intensity λ between noises on the SPD, MFPT, and SNR are discussed, respectively. Research results show that: (i) the high protein level (or ON) state is enhanced (or weaken) by the Ï (or λ); (ii) the MFPT as a function of Q or D exhibits a maximum, which is the signature of the noise enhanced stability (NES) of the ON state. The stability of the ON state can also enhance (or weaken) by the λ (or Ï); (iii) the existence of a maximum and a minimum in the signal-to-noise ratio (SNR) is identifying the characteristics of the SR and stochastic reverse-resonance (SRR) phenomenon, Ï and λ enhance the SR and weaken the SRR phenomenon for SNR as a function of Q, while Ï (or λ) weakens (or enhances) the SR phenomenon for SNR as a function of D; and (iv) the time delay weakens the SR, and causes the SR phenomenon to disappear for SNR as a function of λ.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Chaos, Solitons & Fractals - Volume 96, March 2017, Pages 120-129
Journal: Chaos, Solitons & Fractals - Volume 96, March 2017, Pages 120-129
نویسندگان
Chun Zhang, Liping Du, Tonghuan Wang, Tao Yang, Chunhua Zeng, Canjun Wang,