کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5503563 | 1535291 | 2017 | 37 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Thyroid nodules: Î guide to assessment, treatment and follow-up
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کلمات کلیدی
RAIFTCTSHMTCPTCFNACFine needle aspiration - آسپیراسیون سوزن کاملMRI - امآرآی یا تصویرسازی تشدید مغناطیسیMagnetic resonance imaging - تصویربرداری رزونانس مغناطیسیcomputed tomography - توموگرافی کامپیوتری یا سی تی اسکن یا مقطعنگاری رایانهایPositron emission tomography - توموگرافی گسیل پوزیترونThyroid - تیروئیدThyroglobulin - تیروگلوبولینCancer - سرطانFollicular thyroid cancer - سرطان تیروئید فولیکولارMedullary thyroid cancer - سرطان تیروئید مدولارpapillary thyroid cancer - سرطان پاپیلر تیروئیدfine needle aspiration cytology - سیتولوژی آسپیراسیون سوزنی خوبMen - مردانMultiple endocrine neoplasia - نئوپلازی اندوکرین چندگانهNodule - نودولthyroid stimulating hormone - هورمون محرک تیروئیدPET - پتHyperthyroidism - پرکاری تیروئیدRadioactive iodine - ید رادیواکتیو
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
سالمندی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Thyroid nodules constitute by far the most common disorder of the endocrine system. Epidemiological studies have indicated that approximately 5% of women and 1% of men resident in iodine-sufficient areas have palpable thyroid nodules. However, by the age of 60 years about 50% of the general population is estimated to have at least one thyroid nodule. Indeed, the reported prevalence of a “thyroid incidentaloma” is up to 70% when neck/carotid artery ultrasound, computed tomography (CT) or magnetic resonance imaging (MRI) is performed for other indications. Of those with a nodule, 7-15% will have a thyroid carcinoma. The objective of this article is to present updated information on the definition, prevalence, imaging and functional features of thyroid nodules and to provide guidance on the optimal assessment, treatment and follow-up strategy. The endocrinologist dealing with a patient with a thyroid nodule has to consider two main clinical issues: (i) the possibility of thyroid hormonal excess (hyperthyroidism) and (ii) the risk of malignancy. The former is determined by the assessment of the serum concentrations of thyroid stimulating hormone (TSH), as well as of peripheral thyroid hormones and a thyroid radionuclide scan, if necessary; the latter is achieved by the use of thyroid ultrasonography, as well as fine needle aspiration cytology (FNAC) and serum calcitonin measurement, if necessary. These assessments will guide management, which can vary from simple follow-up to surgical resection. The indications for surgical management, simple follow-up, conservative therapy or treatment with radioactive iodine are discussed.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Maturitas - Volume 96, February 2017, Pages 1-9
Journal: Maturitas - Volume 96, February 2017, Pages 1-9
نویسندگان
Stavroula Î. Paschou, Andromachi Vryonidou, Dimitrios G. Goulis,