کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5510598 | 1539267 | 2017 | 35 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Short-term effects of 17β-estradiol on physiological responses in stellate sturgeon Acipenser stellatus
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شیمی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Short-term effects of 17β-estradiol on physiological responses in stellate sturgeon Acipenser stellatus Short-term effects of 17β-estradiol on physiological responses in stellate sturgeon Acipenser stellatus](/preview/png/5510598.png)
چکیده انگلیسی
There is no evidence of the effect of 17β-estradiol (E2) administration on stress response and related metabolites after a short-period in chondrostean. In this study, we examined whether E2 is capable of inducing the hypothalamus-pituitary-interrenal axis activity. To accomplish this, sexually immature Acipenser stellatus were injected intraperitoneally with saline or E2 (5 mg/kg body mass) and sampled 0, 1, 3, 6, 12, 24, 48, and 72 h later. Plasma E2, cortisol, glucose, lactate, hematocrit (Hct), total protein (TP), cholesterol, triglyceride, alkaline phosphatase activity (ALP), calcium (Ca), and phosphorus concentrations were examined. Plasma levels of E2 significantly increased after 1 h in E2-injected fish and remained high after 12 h. E2 injection enhanced plasma TP and Ca concentrations, but had no effect on other parameters. Injection of either saline or E2 enhanced plasma glucose, lactate, TP, and Ca concentrations, but had no effect on Hct, cholesterol, triglyceride, and ALP. The results demonstrated that acutely elevated level of E2 did not lead to intense changes of stress metabolites and altered biochemical changes compared to the fish in control or saline treatment groups. Therefore, we found no exhibition of E2 on the rate of cortisol synthesis or stress indicators in this species, while E2 could modulate some other related metabolites on vitellogenesis pathway.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology - Volume 195, May 2017, Pages 91-96
Journal: Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology - Volume 195, May 2017, Pages 91-96
نویسندگان
Bahram Falahatkar, Samaneh Poursaeid, Bahman Meknatkhah, Iraj Efatpanah,