Mini-reviewResearch progress in advanced melanoma

- We summarize the most common mutated genes in melanoma.
- The novel regimens in melanoma treatment are listed in the manuscript and the efficacy of each regimen is compared.
- Apart from novel regimens, the potential regimens that may benefit melanoma patients are pointed out, such as anti-angiogenesis inhibitors and vaccines.

Melanoma is a malignant tumor with high rate of metastasis and poor prognosis. How melanoma develops and how to treat it will continue to be a hot topic. This review briefly summarizes the mechanism of melanoma development and the latest progress in its treatment.