کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5529140 1548871 2017 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Case reportHistiocytoid cardiomyopathy and ventricular noncompaction presenting as sudden death in an adult male
ترجمه فارسی عنوان
گزارش موردی کاردیومیوپاتی هیستوکویتوئید و عدم سازگاری بطن چپ به عنوان مرگ ناگهانی در یک مرد بالغ
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی تحقیقات سرطان
چکیده انگلیسی

Histiocytoid/oncocytic cardiomyopathy (HCM) is a rare, distinctive arrhythmogenic disorder that presents as arrhythmia or sudden death in infants and children. Ventricular noncompaction (VNC) is a rare cardiomyopathy characterized by a thickened endocardial layer of noncompacted myocardium and a thin epicardial layer of compacted myocardium. Only six cases of the association of both cardiomyopathies have been reported previously in the literature. All these cases were in children. To the best of our knowledge, a case of HCM has not been described in the adult. We report the case of a 45-year-old man with an increased heart weight and involvement of both ventricles by HCM and VNC cardiomyopathy. Besides, multiple foci of myocardial disorganization were detected. He died suddenly while hiking. The association of both processes HCM and VNC was an unexpected finding at autopsy. The death was linked to functional abnormalities of the cardiac histiocytoid cells, and it was favored by a state of abnormal development of the heart.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Pathology - Research and Practice - Volume 213, Issue 11, November 2017, Pages 1424-1430
نویسندگان
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