کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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5529162 | 1401686 | 2017 | 5 صفحه PDF | دانلود رایگان |
IntroductionA number of new renal tumor entities have been recognized by the 2016 World Health Organization classification of urologic tumors. The classification includes tumors with different behavior and introduces one tumor with low malignant potential, the multilocular cystic clear cell renal cell neoplasm of low malignant potential (mcCCRCNLMP).However, some categories still labeled as “carcinoma”, such as clear cell papillary renal cell carcinoma (CCPRCC), renal angioleiomyomatous tumor (RAT), and tubulocystic carcinoma (TCRCC), all with a particularly good prognosis when diagnosed as low stage, show no malignant behavior: in fact, no metastases have been reported in these categories when surgically excised. Current experience is limited to supporting these neoplasms as benign entities although, recent literature data is defining these entities as “low malignant potential tumors”.Material and methodsWe conducted a search through our files on a consecutive series of 624 renal tumors diagnosed over a period of 2 years to address the incidence of this category of tumors.ResultsApplying strict histological criteria, the “low malignant potential” tumors, comprised 7% of renal masses that are less than 4Â cm in size and 3.8% of renal masses measuring 4â7Â cm in the series of 624 renal tumors. When benign tumors are taken into considerations, the benign and “low malignant potential tumors” represent about one third of renal masses <4Â cm and one sixth of renal masses between 4 and 7Â cm. All these cases have not shown recurrence or metastasis at follow-up, mean follow-up of 18 months (range 6â30 months).ConclusionsThis information may assist urologists in developing guidelines for counseling and proper clinical management for patients with “low malignant potential” tumors or small renal masses.
Journal: Pathology - Research and Practice - Volume 213, Issue 7, July 2017, Pages 804-808