کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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5529493 | 1401700 | 2017 | 7 صفحه PDF | دانلود رایگان |

PurposeAssess the dosimetric impact of multi-leaf collimator (MLC) tracking and mid-ventilation (midV) planning compared with the internal target volume (ITV)-based planning approach for lung Stereotactic Ablative Body Radiotherapy (SABR).MethodTen lung SABR patients originally treated with an ITV-based plan were re-planned according to MLC tracking and midV planning schemes. All plans were delivered on a linac to a motion phantom in a simulated treatment with real lung motions. Delivered dose was reconstructed in patient planning scans. ITV-based, tracking and midV regimes were compared at the planning and delivered stages based on PTV volume and dose metrics for the GTV and OAR.ResultsMLC tracking and midV schemes yielded favourable outcomes compared with ITV-based plans. Average reduction in PTV volume was (MLC tracking/MidV) 33.9%/22%. GTV dose coverage performed better with MLC tracking than the other regimes. Reduction in dose to OAR were for the lung (mean lung dose, 0.8Â Gy/0.2Â Gy), oesophagus (D3Â cc, 1.9Â Gy/1.4Â Gy), great vessels (D10Â cc, 3.2Â Gy/1.3Â Gy), trachea (D4Â cc, 1.1Â Gy/0.9Â Gy), heart (D1Â cc, 2.0Â Gy/0.5Â Gy) and spinal cord (D0.03Â cc, 0.5Â Gy/â0.1Â Gy).ConclusionMLC tracking showed reduction in PTV volume, superior GTV dose coverage and organ dose sparing than MidV and ITV-based strategies.
Journal: Radiotherapy and Oncology - Volume 124, Issue 1, July 2017, Pages 18-24