PTHrP is essential for normal morphogenetic and functional development of the murine placenta

- PTHrP is expressed in the junctional and labyrinth zones of the murine placenta.
- PTHrP is a regulator of placental development and function.
- PTHrP influences trophoblast cell proliferation, survival and differentiation.
- Fetal growth capacity is modulated by PTHrP.
- Lack of PTHrP is associated with reduced placental system A transporter activity.