کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5532504 1401962 2017 17 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
ReviewAspergillus as a versatile cell factory for organic acid production
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم کشاورزی و بیولوژیک (عمومی)
پیش نمایش صفحه اول مقاله
ReviewAspergillus as a versatile cell factory for organic acid production
چکیده انگلیسی


- Aspergilli as fungal cell factories for biobased organic acid production.
- Progresses in genetic engineering of aspergilli for organic acid production.
- Studies on the biosynthesis of organic acids in aspergilli.

Filamentous fungi from the genus Aspergillus are of high importance for biobased organic acid production. So far, a number of Aspergillus strains belonging to phylogenetically distantly related species have been successfully applied in industrial production of organic acids due to their excellent capabilities of secreting high amounts of desired organic acids. For the past decades, numerous efforts have been made to reveal the mechanisms of organic acid biosynthesis in several Aspergillus species and to improve the production of desired organic acids via genetic engineering. This review summarizes the recent breakthroughs in the fundamental understanding of physiological aspects of organic acid accumulation by fungal biocatalysts and highlights the progress in genetic engineering of aspergilli for organic acid production. The challenges for the future applications of aspergilli as commercial cell factories for organic acid production are also discussed.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Fungal Biology Reviews - Volume 31, Issue 1, January 2017, Pages 33-49
نویسندگان
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