کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5532634 1550074 2017 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Life history tradeoffs of pathogens and the treatment principle of antibiogenesis
ترجمه فارسی عنوان
ترکیبات پاتوژن در تاریخ زندگی و اصل درمان آنتی بیوژنز
کلمات کلیدی
آنتی بیوژنز، باکتری، باروری بیماری عفونی، مصلحت تاریخ زندگی، طول عمر، بیماری زا، ویروس،
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیولوژی سلول
چکیده انگلیسی

There are no eternal individual lives so life continues by relaying with reproduction. Consequently, lifespan and fecundity are two essential genetic traits of life. The life history tradeoffs theory holds that there is an inverse relationship between lifespan and fecundity. This paper proposes two new concepts, i.e., “lifespan of pathogens” and treatment of infections by “antibiogenesis”. The lifespan of pathogens is the time limitation of those tiny lives just as other large creatures. Notably, the lifespan of bacterium is the time interval from the cell division by which it is produced to next division by then its life ends and transforms to two new lives, or dies. Antibiogenesis means inhibiting generation of new lives. By the principle of life history tradeoffs, the lifespan of pathogens determines the speed of their proliferations and consequently the modality of infection. The treatment principle of antibiogenesis requires the duration of treatment to be determined by the lifespan of infected pathogens. The life history tradeoffs theory and the two concepts are helpful to understanding the pathobiology and shaping the clinical aspects of infectious diseases.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Genes & Diseases - Volume 4, Issue 3, September 2017, Pages 154-158
نویسندگان
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