کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5534858 1551362 2017 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
ReviewHumoral innate immunity at the crossroad between microbe and matrix recognition: The role of PTX3 in tissue damage
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیولوژی سلول
پیش نمایش صفحه اول مقاله
ReviewHumoral innate immunity at the crossroad between microbe and matrix recognition: The role of PTX3 in tissue damage
چکیده انگلیسی

Innate immunity is involved in regulating inflammatory and tissue repair responses to injury. In particular, humoral innate immunity plays functions related to wound clearance from tissue debris, and regulation of macrophage and stromal cell activities. PTX3, a component of humoral innate immunity, orchestrates tissue repair by interacting with plasminogen and fibrin. Fluid-phase molecules of innate immunity interact with elements of the extracellular matrix, and some of the latter display opsonic activity against certain bacterial species.Thus, recognition of extracellular matrix and microbial components is a recurrent theme in the humoral arm of the innate immune system.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Seminars in Cell & Developmental Biology - Volume 61, January 2017, Pages 31-40
نویسندگان
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