کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5548273 1556485 2017 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Clinical investigations on gastroprotective effects of ethanolic extract of Phyllanthus emblica Linn fruits
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی طب مکمل و جایگزین
پیش نمایش صفحه اول مقاله
Clinical investigations on gastroprotective effects of ethanolic extract of Phyllanthus emblica Linn fruits
چکیده انگلیسی

The ethanolic extract of dried fruits of Phyllanthus emblica Linn. (Euphorbiaceae) was tested for its gastroprotective effects in patients with gastrointestinal disorders. Thirty patients were selected for the study and divided into three groups consisting of ten subjects each. Patients were given the ethanolic extract of P. emblica (Pe.Et), lactose (placebo) and omeprazole for 14 days respectively.The test group received a Pe.Et dose of 500 mg/day in three divided doses, i.e., each capsule contained 166.6 mg PeEt with lactose added making 500 mg per capsule. The dose of ethanolic extract of P. emblica was calculated on the basis of the crude powder of P. emblica used by traditional healers. Capsules of the same colour but filled with 500 mg lactose were given thrice a day to the patients of the negative (placebo) control group. Omeprazole at the recommended dose of (40 mg/day) was given to the patients of the positive control group. A questionnaire and endoscopic based procedures were adopted for investigation. The gastroprotective effects of P. emblica were compared with both the placebo and the omeprazole-treated group.The results of the study showed that Pe.Et alleviated pain, vomiting, sleep disturbances and other associated problems. Gastroscopic evaluations also showed the healing of damaged mucosa. Taken together these findings indicate that the ethanolic extract of P. emblica fruits has gastroprotective effects in humans and justifies its traditional use.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Herbal Medicine - Volume 7, March 2017, Pages 11-17
نویسندگان
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