کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5554123 1403023 2016 13 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
What Can Big Data Offer the Pharmacovigilance of Orphan Drugs?
ترجمه فارسی عنوان
آنچه که داده های بزرگ می توانند داروی مصرف داروهای یتیم را ارائه دهند؟
کلمات کلیدی
اطلاعات بزرگ، ایمنی مواد مخدر، دارو یتیم، داروی حمایتی، بیماری نادر، رسانه های اجتماعی،
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پزشکی و دندانپزشکی (عمومی)
چکیده انگلیسی

The pharmacovigilance of drugs for orphan diseases presents problems related to the small patient population. Obtaining high-quality information on individual reports of suspected adverse reactions is of particular importance for the pharmacovigilance of orphan drugs. The possibility of mining “big data” to detect suspected adverse reactions is being explored in pharmacovigilance generally but may have limited application to orphan drugs. Sources of big data such as social media may be infrequently used as communication channels by patients with rare disease or their caregivers or by health care providers; any adverse reactions identified are likely to reflect what is already known about the safety of the drug from the network of support that grows up around these patients. Opportunities related to potential future big data sources are discussed.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Clinical Therapeutics - Volume 38, Issue 12, December 2016, Pages 2533-2545
نویسندگان
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