کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5554805 | 1558890 | 2016 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Nephrogenesis in organoids to develop novel drugs and progenitor cell based therapies
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب سلولی و مولکولی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
New therapies that are derived from small molecules and stem/progenitor cells should be developed to face the increasing occurrence of end stage renal disease where treatments are currently limited. Over the last decade a significant progress in the knowledge of how the organs are assembled have been made and led to development of novel three-dimensional organoid assays, also for the kidney. Indeed, such organoids provide novel tool to study aspects of drugs nephrotoxicity, openings for renal disease modeling and cell therapy development and may offer solutions for end stage renal disease.
115
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Pharmacology - Volume 790, 5 November 2016, Pages 3-11
Journal: European Journal of Pharmacology - Volume 790, 5 November 2016, Pages 3-11
نویسندگان
Aleksandra Rak-Raszewska, Seppo Vainio,