کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5554812 1558890 2016 12 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Origin and fate of the regenerating cells of the kidney
ترجمه فارسی عنوان
منشا و سرنوشت سلول های بازسازی کلیه
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب سلولی و مولکولی
چکیده انگلیسی

The kidney has the capacity to regenerate itself provided that the damage is limited and the structure of the kidney remains intact. Nevertheless, in disease conditions this potential may be compromised, leading to progression to chronic kidney disease. For development of new therapeutic strategies it is a prerequisite to understand the origin and regulation of the kidney regenerating cells and the processes that underlie maladaptive repair. Because of the complexity of the kidney consisting of a high number of different cell types, it is a complex task to unravel the origin and fate of cells responsible for regeneration. This review summarises the recent and most important advances in identifying regenerating cell populations of the kidney, and highlights the existing controversies.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Pharmacology - Volume 790, 5 November 2016, Pages 62-73
نویسندگان
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