Method of Continuous Monitoring the Passive Rabbit Iris Deformation based on Stereo Vision

Quantification of the relation between passive iris deformation and pressure differences between the anterior and posterior chamber is necessary to diagnose primary angle closure glaucoma. We devised the animal experiment to simulate the total pupil-blocking. We accomplished the experiments using isolated rabbit irises without destroying orbicular structure. 2D image of the iris was screened when the pressure difference was changed. We computed 3D coordinates of rabbit iris based on stereo vision. The 3D data was used for plotting the curves to indicate the relation between passive iris deformation and pressure differences. Experimental results prove that the height of passive deformation of the iris was 0.6 mm when pressure difference was 600 Pa. The passive iris deformation plays an important effect in primary angle closure glaucoma.