کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5555123 1559627 2017 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Sesquiterpenoids from the cultured mycelia of Ganoderma capense
کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت داروسازی، سم شناسی و علوم دارویی داروشناسی
پیش نمایش صفحه اول مقاله
Sesquiterpenoids from the cultured mycelia of Ganoderma capense
چکیده انگلیسی

Eleven new sesquiterpenoids, including eight cadinane-type sesquiterpenoids, Ganodermanol A-H (1-8), and three eudesmane-type sesquiterpenoids, Ganodermanol I-K (9-11), together with three known compounds (12-14), were isolated from the cultured mycelia of Ganoderma capense. Their structures and absolute configurations were identified through combined extensive spectroscopic analysis, circular dichroism (CD), and Mo2(AcO)4-induced CD. Compounds 4 and 9 exhibited moderate cytotoxic activity against the human cancer cell line HCT116 with IC50 values of 16.6 and 12.2 μM, respectively.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Fitoterapia - Volume 118, April 2017, Pages 73-79
نویسندگان
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