کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5560139 1403309 2017 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A protocol for a systematic review to identify allergenic tree nuts and the molecules responsible for their allergenic properties
ترجمه فارسی عنوان
یک پروتکل برای بررسی سیستماتیک برای شناسایی آجیل درختان آلرژیک و مولکول هایی که برای خواص آلرژیک آنها مسئولیت دارند
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک دانش تغذیه
چکیده انگلیسی


- A protocol to systematically review the evidence that tree nuts and their proteins cause IgE-mediated allergies.
- An evidence-based ranking approach is described to identify tree nuts and allergen molecules causing allergic reactions.
- Outcomes will help identify which tree nut species should be included on allergen lists and support select analytical targets.

Food regulations require that tree nuts and derived ingredients are included on food labels in order to help individuals with IgE-mediated allergies to avoid them. However, there is no consensus regarding which tree nut species should be included in this definition and specified on food labels. Allergen detection methods used for monitoring foods target allergen molecules, but it not clear which are the most relevant molecules to choose. A modified population-exposure-comparators-outcome (PECO) approach has been developed to systematically review the evidence regarding (1) which allergenic tree nuts should be included in food allergen labelling lists and (2) which are the clinically relevant allergens which should be used as analytical targets. A search strategy and criteria against which the evidence will be evaluated have been developed. The resulting evidence will be used to rank tree nuts with regards their ability to cause IgE-mediated allergies, and allergen molecules regarding their capacity to elicit an allergic reaction. The results of the systematic review will enable risk assessors and managers to identify tree nut species that should be included in food allergen labelling lists and ensure analytical methods for determination of allergens in foods are targeting appropriate molecules.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Food and Chemical Toxicology - Volume 106, Part A, August 2017, Pages 411-416
نویسندگان
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