کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5582092 1404227 2016 46 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Key Molecular Drivers of Chronic Lymphocytic Leukemia
ترجمه فارسی عنوان
رانندگان مولکولی کلید لوسمی لنفوسیتی مزمن
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیهوشی و پزشکی درد
چکیده انگلیسی
Chronic lymphocytic leukemia (CLL) is an adult neoplastic disease of B cells characterized by variable clinical outcomes. Although some patients have an aggressive form of the disease and often encounter treatment failure and short survival, others have more stable disease with long-term survival and little or no need for theraphy. In the past decade, significant advances have been made in our understanding of the molecular drivers that affect the natural pathology of CLL. The present review describes what is known about these key molecules in the context of their role in tumor pathogenicity, prognosis, and therapy.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Clinical Lymphoma Myeloma and Leukemia - Volume 16, Issue 11, November 2016, Pages 593-606
نویسندگان
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