Benefit on optimal cerebral perfusion pressure targeted treatment for traumatic brain injury patients

The CPPopt-targeted patient-specific management might be useful for stabilizing CA in TBI patients as well as for improving their outcome. Better outcomes were obtained by maintaining CPP in light hyperperfusion condition (up to 10 mm Hg above CPPopt) when CPPopt is in the range of 60-80 mm Hg, and keeping CPP within the range of CPPopt +/− 5 mm Hg when CPPopt is above 80 mm Hg.