کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5583341 1567670 2017 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Hypoxia-inducible-factor-1 in trauma and critical care
ترجمه فارسی عنوان
هیپوکسی-القایی-عامل-1 در تروما و مراقبت های حیاتی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیهوشی و پزشکی درد
چکیده انگلیسی
HIF-1 is a ubiquitous signaling molecule constantly expressed by the body, but is degraded during normoxic conditions. In hypoxic conditions, it persists and is active. Hypoxia is often associated with trauma due to interrupted blood flow, inflammation or other reasons, causing HIF-1 to be active in signaling and recovery. In this review, the function of HIF-1 is examined, as well as its clinical significance with regard to trauma and critical care. Using this information, we then identify potential points of treatment and intervention.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Critical Care - Volume 42, December 2017, Pages 207-212
نویسندگان
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