کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5593939 | 1571146 | 2017 | 20 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Of fish and mirrors: Fluoxetine disrupts aggression and learning for social rewards
ترجمه فارسی عنوان
از ماهی و آینه: فلوکسستین تجاوز و یادگیری برای پاداش های اجتماعی را مختل می کند
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
فیزیولوژی
چکیده انگلیسی
Aggressive signaling is a key social behavior of male Siamese fighting fish (Betta splendens). Successfully establishing a territory and defending it from intruders has direct fitness effects, making Betta splendens a prime model for studies examining the biological underpinnings of aggressive behavior. Current research has outlined serotonin transporter pathways as one key component for the engagement and coordination of aggressive behavior in Betta splendens. Using the selective serotonin reuptake inhibitor fluoxetine, we examined the impact of 10 μmol exposures on associative learning and aggression between mirror and conspecific social reinforcers. Our results provide clear evidence that exposure to fluoxetine reduces aggression and impairs learning independent of social reinforce type. In addition, our results provide support for motor inhibition of aggressive behavior as the main behavioral mechanism of action for fluoxetine. Placed within the broader context of behavioral syndromes, our results, along with others, implicate serotonergic pathways as a key biological correlate of the bold-aggressive phenotype.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Physiology & Behavior - Volume 173, 1 May 2017, Pages 258-262
Journal: Physiology & Behavior - Volume 173, 1 May 2017, Pages 258-262
نویسندگان
Benjamin R. Eisenreich, Susan Greene, Allen Szalda-Petree,