Platelet Transfusion Practices in the ICU

Platelet transfusions were commonly used in the ICU when platelet counts were ≥ 50 × 109/L. One platelet transfusion increased platelet count by 23 × 109/L. One in five transfusions was ineffectual, and ABO incompatibility was identified as a modifiable risk factor. These data can help direct efforts to reduce platelet overuse and improve transfusion quality.