کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5613956 | 1578018 | 2016 | 25 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
The association between Self-Reported Medication Adherence scores and systolic blood pressure control: a SPRINT baseline data study
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موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
سیستم های درون ریز و اتونومیک
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چکیده انگلیسی
We examined baseline data from the Systolic Blood Pressure Intervention Trial (SPRINT) to investigate whether medication adherence, measured by the 8-item Morisky Medication Adherence Scale (MMAS-8), was associated with systolic blood pressure (SBP) and whether MMAS-8 score and number of antihypertensive medications interacted in influencing SBP. A total of 8435 SPRINT participants were included: 21.2% had low adherence (MMAS-8: <6); 40.0% had medium adherence (6 to <8); and 38.8% had high adherence (8). SBP was <140Â mm Hg in 54.6%; 140-160Â mm Hg in 36.6%; and >160Â mm Hg in 8.8%. In multivariable regression, medium vs. low adherence weakly associated with lower SBP (odds ratio: 1.17; confidence interval: 1.04, 1.31). SPRINT eligibility criteria should be considered when interpreting results. Efforts to understand and enhance adherence are crucial to improve population health, and using self-report instruments might be considered for predicting treatment adherence and response in future efficacy trials and for identifying patients for adherence support in clinical practice.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of the American Society of Hypertension - Volume 10, Issue 11, November 2016, Pages 857-864.e2
Journal: Journal of the American Society of Hypertension - Volume 10, Issue 11, November 2016, Pages 857-864.e2
نویسندگان
William E. MD, Olivia N. MD, Robert F. MD, MS, Jill C. MS, Christianne L. MD, MPH, Jeffrey MD, MPH, Ian M. MD, MPH, Leonardo MD, MPH, Alan DO, Donald E. ScD, MSPH, ScM, Molly B. MD, MPH, Eugene MD, Nancy R. PhD, Paul PhD, David C. MD, PhD,