Evaluation of the level of thiol-disulphide homeostasis in patients with mild and severe preeclampsia

- We assessed thiol-disulphide balance with a new colorimetric method recently developed by Erel & Neşelioğlu.
- Native thiol (SH), total thiol (SS + SH) and disulphide (SS) levels were found to be significantly lower in severe pre-eclamptics when compared to mild pre-eclamptics and the control group (p < 0.01).
- Native thiol (SH), total thiol (SS + SH) and disulphide (SS) levels may have been found to be significantly low as there are low serum albumin and total protein in pre-eclamptic patients, especially in severe pre-eclampsia cases.