کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5626364 1579639 2017 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Case ReportSuccessful corpus callosotomy for Doose syndrome
ترجمه فارسی عنوان
گزارش موردی کولوزوتومی کروی موفق برای سندروم داوز
کلمات کلیدی
سندروم داوز، صرع با تشنج مایوکلونیک-اتون، تشنج مایوکلونیک، کولونوسوتومی عضلانی تحریک عصب واگ،
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب تکاملی
چکیده انگلیسی

Doose syndrome (epilepsy with myoclonic-atonic seizures) is an epilepsy syndrome with an incidence of approximately 1-2% of childhood-onset epilepsies. Although this syndrome is associated with multiple types of generalized seizures, the diagnosis is based on the presence of myoclonic-atonic seizures. Eighteen percent of patients have refractory seizures and intellectual disabilities. There have, however, been a few reports on the efficacy of surgical treatment for Doose syndrome.We describe a case of Doose syndrome in a 10-year-old boy. He developed generalized tonic-clonic seizures at 3 years 8 months of age and subsequently developed myoclonic-atonic, myoclonic, and tonic seizures. The frequent myoclonic seizures were refractory to multiple antiepileptic medications. His cognitive development was moderately delayed. Anterior four fifths corpus callosotomy was performed at 8 years 5 months of age. His seizures, especially myoclonic seizures, were markedly reduced. He was given vagus nerve stimulation therapy at 9 years and 1 month of age, which led to complete resolution of the myoclonic seizures. Corpus callosotomy can be a good treatment strategy in patients with Doose syndrome with medically refractory generalized seizures.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Brain and Development - Volume 39, Issue 10, November 2017, Pages 882-885
نویسندگان
, , , , , , , , ,