کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5628892 1580000 2017 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Severe methemoglobinemia caused by continuous lidocaine infusion in a term neonate
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب تکاملی
پیش نمایش صفحه اول مقاله
Severe methemoglobinemia caused by continuous lidocaine infusion in a term neonate
چکیده انگلیسی
Neonates and young infants are especially prone to develop drug-induced methemoglobinemia. Therefore, lidocaine is not licensed as local anesthetic in children below the age of 3 months. However, its systemic use is advocated for neonatal seizures. Cardiac arrhythmia has been reported as sole major side effect. Here we report a case of severe methemoglobinemia caused by continuous infusion of lidocaine in a term neonate with neonatal seizures. The increase of methemoglobin up to 13.8% was accompanied by hypoxemia and cyanosis, necessitating additional inspired oxygen and CPAP ventilation. After stopping lidocaine infusion methemoglobin levels fell and the neonate could be weaned from ventilation. Neonates treated with lidocaine for seizures must be monitored for the occurrence of methemoglobinemia.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Paediatric Neurology - Volume 21, Issue 3, May 2017, Pages 576-579
نویسندگان
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