Ganglion cell complex loss precedes retinal nerve fiber layer thinning in patients with pituitary adenoma

- A new pattern of retinal ganglion thickness changes over time in patients with pituitary adenoma is proposed.
- Ganglion cell complex thinning was shown in patients without optic chiasma compression.
- Retinal nerve fiber layer thinning was shown only in patients with large tumors and severe optic chiasma distortion.