کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5629930 | 1580277 | 2017 | 5 صفحه PDF | دانلود رایگان |
- Miller Fisher syndrome (MFS) is a rare variant of Guillain-Barré syndrome (GBS).
- Cranial nerve involvement is not infrequent in MFS.
- Optic nerves/pathways can show abnormal enhancement.
- Imaging findings do not always correlate with clinical cranial nerve involvement.
Background: Miller Fisher syndrome (MFS) is a rare demyelinating condition which may have involvement of cranial nerves. There are a few case reports of optic pathway involvement in children. We describe 3 patients with optic pathway enhancement in pediatric patients with MFS. Case series: We retrospectively reviewed brain imaging findings in 17 pediatric patients with of Guillain-Barré syndrome (GBS) meeting Brighton criteria who had brain MRIs performed during their acute illness. Cranial nerve enhancement was seen in 6/17 patients and optic nerve/chiasm enhancement was seen in 3 patients. Conclusion: Cranial nerve enhancement and optic pathway in particular, can be seen in patients with MFS. Imaging findings do not always correlate with clinical manifestations of cranial nerve involvement.
Journal: Journal of Clinical Neuroscience - Volume 39, May 2017, Pages 63-67