کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5629939 | 1580277 | 2017 | 4 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Case reportSphenoid sinus carcinoid tumour causing ectopic ACTH syndrome Case reportSphenoid sinus carcinoid tumour causing ectopic ACTH syndrome](/preview/png/5629939.png)
A thirty-eight year old patient presented with a gradual increase in weight and Cushingoid facies of two years duration. He also had orbital congestion, with puffy eyelids and corkscrew conjunctival vessels, associated with painful eye movements. An endocrine evaluation revealed raised cortisol and ACTH. Head imaging was performed which showed an enhancing tumour arising from the sphenoid sinus, with osseous erosion of the sphenoid sinus, extending to the nasopharynx, sellar and a small amount extending intracranially. He underwent an endoscopic endonasal resection of the tumour and histology revealed a low-grade carcinoid tumour with ACTH staining. The patient also underwent radiotherapy for the intracranial extension. He is currently in his fourth year of follow-up and imaging has showed a small, stable intracranial remnant. His anterior pituitary hormonal profile remains normal.
Journal: Journal of Clinical Neuroscience - Volume 39, May 2017, Pages 92-95