Guillain-Barré syndrome in north-western India: Demographic, clinical, electrophysiological profile and assessment of prognostic factors

Most common variant in our study was acute motor axonal neuropathy (41.6%) while the most common age group was 15-29 years. There was history of antecedent event in 22 patients (37%) and sensory deficit in 31.7% (proprioceptive > exteroceptive). Cranial nerve involvement was seen in 40% (facial > bulbar > ophthalmoplegia) and autonomic dysfunction in 11.7%. Respiratory involvement was seen in 22 patients (36.7%). Nerve conduction abnormalities were observed in 96% of the cases. Sural sparing was found in 15% of cases at admission predominantly in acute inflammatory demyelinating polyneuropathy and F-wave abnormality (prolonged/delayed) in 72% of patients at admission which was most frequently seen in peroneal nerve. Severity at admission (high GBS disability score), need for ventilation, high modified Erasmus GBS outcome score were associated significantly (p-value <0.05) while age (>55 years) and axonal lesion were non-significantly (p-value >0.05) with poor outcome.