کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5638798 | 1584098 | 2017 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Do antiplatelet drugs increase the risk of bleeding after tooth extraction? A case-crossover study
ترجمه فارسی عنوان
آیا داروهای ضد ترومبوز پس از استخراج دندان خطر خونریزی را افزایش می دهند؟ مطالعه موردی متقاطع
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کلمات کلیدی
آسپرین کلوپیدوگرل، کشیدن دندان، خون ریزی،
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
دندانپزشکی، جراحی دهان و پزشکی
چکیده انگلیسی
The aim of this study was to assess the risk of bleeding after tooth extraction in patients taking aspirin or clopidogrel. This case-crossover study evaluated patients taking aspirin (80Â mg/day) or clopidogrel (75Â mg/day) and undergoing tooth extraction. In the first session, extraction was performed without discontinuing aspirin (group 1) or clopidogrel (group 2). In the second session, patients ceased using antiplatelet drugs 5Â days prior to tooth extraction. Bleeding was evaluated using a visual analogue scale (VAS) for 72Â h after tooth extraction. The platelet function assay (PFA) was performed for group 1 and flow cytometry assessment of vasodilator-stimulated phosphoprotein (VASP) was performed for group 2, in both sessions. Thirty-eight patients were studied: 20 in group 1 and 18 in group 2. Analysis of the data did not demonstrate any difference in bleeding severity between sessions 1 and 2 in either group (PÂ >Â 0.05). There was a significant difference between sessions 1 and 2 in group 1 for the mean collagen/epinephrine membrane closure time (PFA) (PÂ =Â 0.001). A significant difference in platelet reactivity index (flow cytometry for VASP) was noted between sessions 1 and 2 in group 2 (PÂ =Â 0.001). According to this case-crossover study, dental extraction can be performed safely without withdrawal of aspirin or clopidogrel.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Oral and Maxillofacial Surgery - Volume 46, Issue 11, November 2017, Pages 1475-1478
Journal: International Journal of Oral and Maxillofacial Surgery - Volume 46, Issue 11, November 2017, Pages 1475-1478
نویسندگان
F. Akhlaghi, I. Khaheshi, S. Amirhassani, R. Tabrizi,