Multidisciplinary management of stage IV colon cancer

Significant advances in systemic chemotherapy and surgical techniques have allowed a subset of patients with stage IV colorectal cancer to be suitable candidates for multimodality therapy with curative intent. Care of these patients requires multidisciplinary coordination, close monitoring of disease response, and individualized treatment plan. This review will discuss considerations for treatment planning and sequencing in patients with symptomatic and asymptomatic primary colon cancer in the setting of potentially resectable liver metastases.