کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5669605 1592477 2017 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Mielitis y lupus: clínica, diagnóstico y tratamiento. Revisión
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی ایمونولوژی، آلرژی و روماتولوژی
پیش نمایش صفحه اول مقاله
Mielitis y lupus: clínica, diagnóstico y tratamiento. Revisión
چکیده انگلیسی
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that affects multiple systems. Myelopathy is one of 19 neuropsychiatric syndromes related to SLE defined by the American College of Rheumatology. Although infrequent, it is a severe manifestation, leading to motor and sensory deficits, and sphincter dysfunction. The pathogenesis is not clearly known, but may be related to arterial thrombosis and vasculitis. Diagnosis is based on clinical findings, laboratory tests and the use of gadolinium-enhanced magnetic resonance imaging. The standard therapy is the combination of intravenous cyclophosphamide and glucocorticoids. In refractory disease, other treatments such as plasmapheresis or rituximab have been used.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Reumatología Clínica - Volume 13, Issue 6, November–December 2017, Pages 344-348
نویسندگان
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