کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5672865 | 1408127 | 2017 | 5 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Comparison of Xpert® HPV and Hybrid Capture® 2 DNA Test⢠for detection of high-risk HPV infection in cervical atypical squamous cells of undetermined significance Comparison of Xpert® HPV and Hybrid Capture® 2 DNA Test⢠for detection of high-risk HPV infection in cervical atypical squamous cells of undetermined significance](/preview/png/5672865.png)
SummaryThis study compares Xpert® HPV and Hybrid Capture® 2 High-Risk HPV DNA Test⢠(hc2) for the detection of high-risk HPV infection in cervical smears. Papanicolaou smears with atypical squamous cells of undetermined significance (ASC-US) constituted the study specimens. Of the 168 ASC-US samples, 134 (79.8%) were from Saudi patients. The hc2 test was positive in 33 (19.6%) of the total patients, 20% among Saudi patients, and 17.6% among non-Saudi patients. Xpert® HPV produced positive results in 30 (17.8%) of the samples. The overall concordance rate between the two tests was 98.2%, and the positive concordance rate was 91%. There were three samples tested positive by hc2 that tested negative by Xpert® HPV. HPV 16, HPV 18/45 and HPV other types were the most common types. Both tests have a reasonable positive concordance rate, although hc2 detected more cases than Xpert® HPV. Xpert® HPV provides a viable alternative to the hc2 test with similar detection results for samples with ASC-US.
Journal: Journal of Infection and Public Health - Volume 10, Issue 2, MarchâApril 2017, Pages 219-223