کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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5679915 | 1408680 | 2017 | 7 صفحه PDF | دانلود رایگان |
Background/PurposeExtracorporeal membrane oxygenation (ECMO) is a treatment option for stabilizing neonates with congenital diaphragmatic hernia (CDH) in a critical condition when standard therapy fails. However, the use of this approach in Taiwan has not been previously reported.MethodsThe charts of all neonates with CDH treated in our institute during the period 2007-2014 were reviewed. After 2010, patients who could not be stabilized with conventional treatment were candidates for ECMO. We compared the demographic data of patients with and without ECMO support. The clinical course and complications of ECMO were also reviewed.ResultsWe identified 39 neonates with CDH with a median birth weight of 2696Â g (range, 1526-3280Â g). Seven (18%) of these patients required ECMO support. The APGAR score at 5Â minutes differed significantly between the ECMO and non-ECMO groups. The survival rate was 84.6% (33/39) for all CDH patients and 57.1% (4/7) for the ECMO group. The total ECMO bypass times in the survivors was in the range of 5-36Â days, whereas all nonsurvivors received ECMO for at least 36Â days (mean duration, 68Â days). Surgical bleeding occurred in four of seven patients in the ECMO group.ConclusionThe introduction of ECMO rescued some CDH patients who could not have survived by conventional management. Prolonged (i.e., > 36Â days) ECMO support had no benefit for survival.
Journal: Journal of the Formosan Medical Association - Volume 116, Issue 5, May 2017, Pages 333-339