Optimizing the antisepsis protocol: Effectiveness of 3 povidone-iodine 1.0% applications versus a single application of povidone-iodine 5.0%

Povidone-iodine 5.0% has been the standard of care for preoperative ocular antisepsis for 3 decades. Povidone-iodine 0.7% was as effective as a bactericidal agent when applied multiple times. This suggests povidone-iodine 1.0%, applied in three 30-second applications for preoperative surface disinfection might be as effective for preoperative antisepsis.