کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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5714862 | 1605970 | 2017 | 5 صفحه PDF | دانلود رایگان |
ObjectivesThe prevalence of hearing loss (HL) in children infected with HIV/AIDS is not well studied. Even fewer studies focus on stable HIV-infected children treated with high-effective antiretroviral therapy (HAART). We aim to compare the prevalence of ear disease and HL in HAART-treated, HIVÂ +Â children in Addis Ababa, Ethiopia with a well, similarly-aged elementary school population with unknown HIV status (HIVU).MethodsChildren underwent standard head and neck examination and cerumen removal by board certified otolaryngologists. Next, certified audiologists performed hearing screening with pure-tone audiometry using a circumaural headset but without an ambient noise reducing environment. Children failing audiometric screening underwent full behavioral audiometry including air and bone testing. The primary outcome parameter was HLÂ >Â 25Â dB with the audiologist accounting for background noise. A second endpoint was PTA >40Â dB (500, 1000, 2000Â Hz) without assessment of background noise.Results107 HIV+ and 147 HIVU children met inclusion criteria. In the HIVÂ +Â cohort 17.8% had evidence of TM perforations and 8.4% had otorrhea. In the HIVU group 2.7% had a TM perforation and 0% had otorrhea. Hearing was significantly worse in HIVÂ +Â children. (Audiologist determination: 38.3% HL HIV+, 12.2% HIVU, Fisher's-Exact-Test OR: 4.5, 95% CI 2.4-8.3, p-value <0.0001; Worse-hearing-ear PTAÂ >Â 40Â dB: 19.6% HL HIV+, 6.1% HIVU, OR: 3.7, 95% CI 1.7-8.4, p-value <0.001).ConclusionsChronic OM, conductive and mixed hearing losses are significantly more common in HAART-treated HIVÂ +Â children than in well, similarly-aged controls. Rates of SNHL are similar.
Journal: International Journal of Pediatric Otorhinolaryngology - Volume 98, July 2017, Pages 166-170