کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5736393 | 1613225 | 2017 | 26 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
The effects of Chinese medicines on cAMP/PKA signaling in central nervous system dysfunction
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب سلولی و مولکولی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: The effects of Chinese medicines on cAMP/PKA signaling in central nervous system dysfunction The effects of Chinese medicines on cAMP/PKA signaling in central nervous system dysfunction](/preview/png/5736393.png)
چکیده انگلیسی
Neuropathological injury in the mammalian adult central nervous system (CNS) may cause axon disruption, neuronal death and lasting neurological deficits. Failure of axon regeneration is one of the major challenges for CNS functional recovery. Recently, the cAMP/PKA signaling pathway has been proven to be a critical regulator for neuronal regeneration, neuroplasticity, learning and memory. Also, previous studies have shown the effects of Chinese medicines on the prevention and treatment of CNS dysfunction mediated in part by cAMP/PKA signaling. In this review, the authors discuss current knowledge of the role of cAMP/PKA signaling pathway in neuronal regeneration and provide an overview of the Chinese medicines that may enable CNS functional recovery via this signaling pathway.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Brain Research Bulletin - Volume 132, June 2017, Pages 109-117
Journal: Brain Research Bulletin - Volume 132, June 2017, Pages 109-117
نویسندگان
Lin Li, Xiang Fan, Xi-Ting Zhang, Shao-Qian Yue, Zuo-Yan Sun, Jin-Qiang Zhu, Jun-Hua Zhang, Xiu-Mei Gao, Han Zhang,