Cortical interneuron specification: the juncture of genes, time and geometry

- The GEs produce many types of GABAergic projection neurons and a majority of GABAergic interneurons.
- Spatial origin, birthdate, and mode of division influence interneuron fate.
- Subdomains exist within each GE, producing different neuronal subtypes over time.
- PV and SST-expressing interneurons can originate from the same progenitor.
- Different modes of divisions are biased for producing different interneuron subtypes.