کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5737394 | 1614711 | 2017 | 11 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Adaptation facilitates spatial discrimination for deviant locations in the thalamic reticular nucleus of the rat
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
ROCSSASOPCSISSPSPLperi-stimulus time histogramsPSTHsMMNAUC - AUCISI - آی اس آیStimulus-specific adaptation - انطباق خاص محرکERP - برنامه ریزی منابع سازمانbest frequency - بهترین فرکانسSound pressure level - سطح فشار صوتinter-stimulus interval - فاصله بین محرکAuditory Cortex - قشر شنواییarea under curve - منطقه تحت منحنیmismatch negativity - ناسازگاری منفیEvent-related potential - پتانسیل وابسته به رویدادInferior colliculus - کولیکولوس پایینreceiver operating characteristic - گیرنده عامل عامل
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب (عمومی)
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
The capacity to identify unanticipated abnormal cues in a natural scene is vital for animal survival. Stimulus-specific adaptation (SSA) has been considered the neuronal correlate for deviance detection. There have been comprehensive assessments of SSA in the frequency domain along the ascending auditory pathway, but only little attention given to deviance detection in the spatial domain. We found that thalamic reticular nucleus (TRN) neurons exhibited stronger responses to a tone when it was presented rarely as opposed to frequently at a certain spatial location. Subsequently, we engaged signal detection theory to directly gauge neuronal spatial discriminability and found that discrimination of deviant locations was considerably higher than standard locations. The variability in neuronal spatial discriminability among the TRN population was directly related to response difference (RD) but not variance; meanwhile, further analyses attributed higher spatial sensitivity at deviant locations to larger RD. Astonishingly, a significant correlation was found between the amount of adaptation and deviant discriminability. Collectively, our results suggest that adaptation facilitates rare location discrimination by sharpening the response gap between two locations.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuroscience - Volume 365, 4 December 2017, Pages 1-11
Journal: Neuroscience - Volume 365, 4 December 2017, Pages 1-11
نویسندگان
Xin-Xiu Xu, Yu-Ying Zhai, Xiao-Kai Kou, Xiongjie Yu,