کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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5808759 | 1556077 | 2011 | 7 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Antifungal efficacy of Brazilian green propolis extracts and honey on Tinea capitis and Tinea versicolor Antifungal efficacy of Brazilian green propolis extracts and honey on Tinea capitis and Tinea versicolor](/preview/png/5808759.png)
Aim of the studyThis study aimed to determine the prevalence of Tinea capitis and Tinea versicolor, and evaluate the efficacy of bee products in management of skin disorders in Congolese school children.MethodologyMedical screening and care for skin disorders were carried out in five Congolese schools from November 2010 to April 2011. Hematological and mycological analyses were performed. Of the 2728 children, there were 305 patients with either Tinea capitis or Tinea versicolor. Of them, 242 eligible patients were randomly allocated to one of the following topical treatment arms: 2% Miconazole; 50 mg/ml Brazilian green propolis extracts (BPE); 100 mg/ml BPE; Acasia honey or Vaseline. Oneway ANOVA test was performed to assess the significance of the difference between treatment groups at baseline (day 1), adjusting for age, gender and the severity score of skin symptoms. Unpaired t-test was performed to assess the difference between treatments in terms of skin symptoms improvement, WBC count, leukocytes and erythrocytes sedimentation rate (ESR) on day 28 of treatment.ResultsThis study showed that Miconazole (p < 0.01), both BPE solutions and Acasia honey (p < 0.05) markedly improved erythema and desquamation (vs. Vaseline). In addition, 100 mg/ml BPE, 50 mg/ml BPE, Miconazole and Acasia honey (p < 0.05) also significantly relieved pruritus (vs. Vaseline). No major adverse effect was observed throughout the study.ConclusionsBrazilian green propolis extracts improved skin lesions as efficiently as did Miconazole and may serve as an alternative treatment for Tinea mycosis.
Journal: European Journal of Integrative Medicine - Volume 3, Issue 4, December 2011, Pages e281-e287