کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5812101 | 1115027 | 2013 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Mediterranean diet and the Spanish paradox. A hypothesis
ترجمه فارسی عنوان
رژیم مدیترانه و پارادوکس اسپانیایی. یک فرضیه
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موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شناسی تکاملی
چکیده انگلیسی
The Spanish paradox is a phenomenon observed in Spain and some other Mediterranean countries by which the cardiovascular morbidity and mortality levels are dissociated from their cardiovascular risk factors. The Mediterranean diet has been proposed as the main reason for this dissociation, but dietary changes themselves are not enough to explain this situation. It has been recently discovered that Stearoil-CoA desaturase (SCD) is involved in the dissociation between a favourable atherogenic metabolic profile and the risk for arteriosclerosis. We propose a hypothesis that attempts to clarify the Spanish paradox. This hypothesis contemplates the essential role of dietary olive oil and its interaction with different SCD genetic patterns. Confirmation of this hypothesis could provide the basis for the design of clinical and preventive strategies against cardiovascular morbidity and mortality, as well as certain metabolic risk factors.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Medical Hypotheses - Volume 80, Issue 2, February 2013, Pages 150-155
Journal: Medical Hypotheses - Volume 80, Issue 2, February 2013, Pages 150-155
نویسندگان
Federico Soriguer, Eva GarcÃa-Escobar, Sonsoles Morcillo, Eduardo GarcÃa-Fuentes, Fernando RodrÃguez de Fonseca, Gabriel Olveira, Gemma Rojo-MartÃnez,