Anti-tumour and pharmacokinetics study of 2-Formyl-8-hydroxy-quinolinium chloride as Galipea longiflora alkaloid analogue

2-Formyl-8-hydroxy-quinolinium chloride was prepared as Galipea longiflora alkaloid analogue and its anticancer activity was evaluated. Representative histopathological sections showed (a) significant tumour necrosis could be identified in 2-Formyl-8-hydroxy-quinolinium chloride-treated group while (b) good cellular integrity could be observed in vehicle treated group on day 23 (10 days after stopping the treatment).