کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5831406 | 1559661 | 2013 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Triterpenoid saponins from Clematis tangutica and their cardioprotective activities
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موضوعات مرتبط
علوم پزشکی و سلامت
داروسازی، سم شناسی و علوم دارویی
داروشناسی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Phytochemical investigation of the whole plants of Clematis tangutica led to the isolation of three new triterpenoid saponins (1-3), together with four known saponins (4-7). Their structures were determined by extensive spectral analysis and chemical evidences. Compounds 1-7 were evaluated for their cardioprotective activities in cardiomyocytes anoxia/reoxygenation (A/R) model. The results showed that those saponins exhibited cardioprotective effects by decreasing the levels of creatine kinase-MB (CK-MB) and lactate dehydrogenase (LDH).
Three new triterpenoid saponins (1-3), together with four known ones (4-7) were isolated from the whole plants of Clematis tangutica. These saponins exhibited cardioprotective effects.97
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Fitoterapia - Volume 84, January 2013, Pages 326-331
Journal: Fitoterapia - Volume 84, January 2013, Pages 326-331
نویسندگان
Wei Zhang, Xiaoyang Wang, Haifeng Tang, Minchang Wang, Lanju Ji, Aidong Wen, Jianbo Wang,